A computational model of teeth and the developmental origins of morphological variation

@article{SalazarCiudad2010ACM,
  title={A computational model of teeth and the developmental origins of morphological variation},
  author={Isaac Salazar-Ciudad and Jukka Jernvall},
  journal={Nature},
  year={2010},
  volume={464},
  pages={583-586}
}
The relationship between the genotype and the phenotype, or the genotype–phenotype map, is generally approached with the tools of multivariate quantitative genetics and morphometrics. Whereas studies of development and mathematical models of development may offer new insights into the genotype–phenotype map, the challenge is to make them useful at the level of microevolution. Here we report a computational model of mammalian tooth development that combines parameters of genetic and cellular… 

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