A computational model for the optimization of transport phenomena in a rotating hollow-fiber bioreactor for artificial liver.

@article{Consolo2009ACM,
  title={A computational model for the optimization of transport phenomena in a rotating hollow-fiber bioreactor for artificial liver.},
  author={Filippo Consolo and Gianfranco Beniamino Fiore and Silvia Truscello and Marco Caronna and Umberto Morbiducci and Franco M. Montevecchi and Alberto Redaelli},
  journal={Tissue engineering. Part C, Methods},
  year={2009},
  volume={15 1},
  pages={41-55}
}
A comprehensive computational study modelling the operation of a rotating hollow-fiber bioreactor for artificial liver (BAL) was performed to explore the interactions between the oxygenated culture medium and the cultured hepatocytes. Computational fluid dynamics investigations were carried out using two-dimensional (2D) and 3D time-dependent numerical simulations, integrating calculations of diffusion, convection, and multiphase fluid dynamics. The analysis was aimed at determining the… CONTINUE READING
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