A comprehensive survey of polymorphisms conferring anti-malarial resistance in Plasmodium falciparum across Pakistan

@inproceedings{Khattak2013ACS,
  title={A comprehensive survey of polymorphisms conferring anti-malarial resistance in Plasmodium falciparum across Pakistan},
  author={Aamer A Khattak and Meera Venkatesan and Christopher G. Jacob and Elena M Artimovich and Muhammad F Nadeem and Farida Nighat and Francis Wanak Hombhanje and Toshihiro Mita and Salman A. Malik and Christopher V. Plowe},
  booktitle={Malaria Journal},
  year={2013}
}
Few studies have been conducted in Pakistan to determine the efficacy of chloroquine and sulphadoxine-pyrimethamine (SP), which remain in use as treatment for Plasmodium vivax and in combination with artesunate to treat Plasmodium falciparum, respectively. In this study, samples from several sites across Pakistan were characterized to determine prevalence of molecular resistance markers in the P. falciparum chloroquine resistance transporter (pfcrt), multidrug resistance (pfmdr1), dihydrofolate… CONTINUE READING
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