Corpus ID: 80220155

A comprehensive pharmacognostic report on Valerian.

  title={A comprehensive pharmacognostic report on Valerian.},
  author={Mukti Sharma and Uttam Jain and Ajay I. Patel and Nilesh Gupta},
  journal={International Journal of Pharmaceutical Sciences and Research},
Herbalism is a traditional medicine practice based on the utilization of plants and plant extracts. In herbalism ‘Valerian’ is a boon medicine for several ailments. Valerian (Valerian officinalis) is a naturally occurring Ayurvedic medicine widely grown in the temperate zones of Europe, North America and Asia and is a safe herbal supplement indicated in various ailments, chief being for the symptoms associated with difficulty in sleeping. It improves subjective experiences of sleep when taken… Expand
Valeriana spp.: Biological Activities and New In vitro and In vivo Perspectives
This review summarizes and updates the current knowledge about the pharmacological properties of valerian, highlighting the most recent clinical, in vitro and in vivo findings, and intends to identify and propose future directions for further research regarding the effective biological effects of Valeriana spp. Expand
Chemical constituents and antihistamine activity of Bixa orellana leaf extract
The experimental findings demonstrated that the anti-inflammatory activity of AEBO was due to its inhibitory effect on vascular permeability, which was suppressed as a result of the reduced expression of biochemical mediators (NO and VEGF) in tissues. Expand
A Review on Medicinal Plants Used for Nausea and Vomiting in Persian Medicine
The most medicinal plants for the treatment of nausea and vomiting were: Citrus lemon, Berberis vulgaris, Malus domestica, Mentha piperita, Valeriana officinalis and Zingiber officinale. Expand
Phytotherapy of Opioid Dependence and Withdrawal Syndrome: A Review
The effects of plant extracts and active components on morphine dependence and withdrawal syndrome are discussed and plants from Lamiaceae, Ranunculaceae, and Apiaceae families were especially effective. Expand
Plant Bioactives and Extracts as Feed Additives in Horse Nutrition
Engaging plant extracts as feed additives is considered to be safe in equines, and few considerations should be given for dosage of the drug, period of administration, apart from monitoring parallel drugs given to prevent herb‐drug interactions. Expand
Transcriptome and metabolome analysis in shoot and root of Valeriana fauriei
The transcriptome is identified using Illumina HiSeq system in shoot and root of V. fauriei and gene expressions associated with secondary metabolism such as terpenoid, carotenoid, and phenylpropanoid are demonstrated. Expand
Suppressions of Serotonin-Induced Increased Vascular Permeability and Leukocyte Infiltration by Bixa orellana Leaf Extract
Pharmacological screening of the extract showed significant anti-inflammatory activity, indicated by the suppressions of increased vascular permeability and leukocyte infiltration, which is probably mediated via inhibition of NO and VEGF formation and release. Expand
Volatile Constituents of Cnidium silaifolium (Jacq.) Simonkai subsp. Orientale (Boiss.) Tutin from Turkey
Abstract The oil obtained by hydrodistillation from the aerial parts of Cnidium silaifolium (JACQ.) Simonkai subsp. orientale (Boiss.) Tutin from Turkey was analyzed by GC and GC-MS. Twenty fiveExpand
Effect of valerian on cognitive disorders and electroencephalography in hemodialysis patients: a randomized, cross over, double-blind clinical trial
The findings of this study indicated that valerian could be effective and significantly improve patients’ cognitive status; however, no significant changes were observed in the electroencephalography of the hemodialysis patients. Expand
Metabolic analysis reveals temporal changes in C/N metabolites and senescence of flag leaf in wheat during grain filling
  • Yan Zhang, Wanying Du, +5 authors Lingan Kong
  • Chemistry
  • Acta Physiologiae Plantarum
  • 2021
Flag leaves have been considered to be the first key organ contributing to higher yields in triticeae crops. Therefore, dynamical changes in physiological metabolisms in flag leaves are important toExpand


Valeriana officinalis Monograph
Description Valerian is the common name for over 250 worldwide plant species of the genus Valeriana (Valerianaceae). Although all of the species’ roots contain similar medicinal constituents andExpand
The Scientific Basis for the Reputed Activity of Valerian
  • P. Houghton
  • Biology, Medicine
  • The Journal of pharmacy and pharmacology
  • 1999
The underground organs of members of the genus Valeriana (Valerianaceae), as well as related genera such as Nardostachys, are used in the traditional medicine of many cultures as mild sedatives andExpand
Herbal Drugs and Phytopharmaceuticals: A Handbook for Practice on a Scientific Basis
This new edition of Herbal Drugs and Phytopharmaceuticals takes the advances made in medicinal plants research and phytotherapy into account and offers reliable, highly pertinent information. Expand
Valerian: Practical Management of Adverse Effects and Drug Interactions
The rhizomes or roots of this plant are used in a variety of forms, including capsules, extracts, teas, and tinctures, and in combination with other herbs such as hops, kava, and skullcap. Expand
[Valeriana officinalis and Crataegus oxyacantha: toxicity from repeated administration and pharmacologic investigations].
The aim of this work is to study the toxicity of Valeriana officinalis and Crataegus oxyacantha after reiterated administrations with influence of drugs on the behaviour, the pain, the intestinal peristalsis and strychnine convulsions. Expand
The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines
This book is a translation of all 380 monographs on medicinal herbs published by the German commission E, an expert multidisciplinary group within the German federal health agency charged with evaluating the safety and efficacy of herbal medications. Expand
Pharmacological screening of valerenal and some other components of essential oil of Valeriana officinalis.
Valerenal and valerenic acid are pharmacologically active at the lowest dose levels and together with valeranone are likely to play a significant role in the depressive action of the essential oil whereas the activity of isoeugenyl-isovalerate is of relatively minor importance. Expand
Valeriana officinalis et Crataegus oxyacantha: toxicité par administrations réitérées et investigations pharmacologiques.
The aim of this work is to study the toxicity of Valeriana officinalis and Crataegus oxyacantha after reiterated administrations by pharmacological properties which are related to the two plants. Expand
Herbal remedies in psychiatric practice.
In many cases the quantity and quality of data were insufficient to make definitive conclusions about efficacy or safety, but there was good evidence for the efficacy of St John's wort for the treatment of depression and for ginkgo in the Treatment of memory impairment caused by dementia. Expand
Valeriana officinalis: traditional used and recent evaluation of activity
Clinical studies substantiate the use of valerian preparations for sleep disorders and stress situations and the interaction of total extracts and some purified fractions of V. officinalis with the inhibitory neurotransmitter γ-aminobutyric acid (GABA). Expand