A comprehensive next generation sequencing-based virome assessment in brain tissue suggests no major virus - tumor association

@inproceedings{Strong2016ACN,
  title={A comprehensive next generation sequencing-based virome assessment in brain tissue suggests no major virus - tumor association},
  author={Michael J Strong and Eugene E. Blanchard and Zhen Lin and Cindy A. Morris and Melody C. Baddoo and Christopher M Taylor and Marcus L. Ware and Erik K. Flemington},
  booktitle={Acta neuropathologica communications},
  year={2016}
}
Next generation sequencing (NGS) can globally interrogate the genetic composition of biological samples in an unbiased yet sensitive manner. The objective of this study was to utilize the capabilities of NGS to investigate the reported association between glioblastoma multiforme (GBM) and human cytomegalovirus (HCMV). A large-scale comprehensive virome assessment was performed on publicly available sequencing datasets from the Cancer Genome Atlas (TCGA), including RNA-seq datasets from primary… CONTINUE READING
Highly Cited
This paper has 42 citations. REVIEW CITATIONS