A comprehensive immunological analysis in chronic fatigue syndrome.

  title={A comprehensive immunological analysis in chronic fatigue syndrome.},
  author={Sudhir Gupta and Bharathi Vayuvegula},
  journal={Scandinavian journal of immunology},
  volume={33 3},
A detailed analysis of cell-mediated and antibody-mediated immunity was performed in 20 CDC-defined patients with chronic fatigue syndrome (CFS) and 20 age- and sex-matched healthy controls. CD3+, CD4+, CD8+, and CD20+ lymphocytes were comparable in two groups. Natural killer cells as defined by CD16, CD56 and CD57 antigens were significantly reduced in CFS. A significant increase in the proportions of CD4+ ICAM 1+ T cells was observed in CFS. Monocytes from CFS displayed increased density (as… CONTINUE READING


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