A comprehensive guide to pilus biogenesis in Gram-negative bacteria

  title={A comprehensive guide to pilus biogenesis in Gram-negative bacteria},
  author={Manuela Kathrin Hospenthal and Tiago R. D. Costa and Gabriel Waksman},
  journal={Nature Reviews Microbiology},
Pili are crucial virulence factors for many Gram-negative pathogens. These surface structures provide bacteria with a link to their external environments by enabling them to interact with, and attach to, host cells, other surfaces or each other, or by providing a conduit for secretion. Recent high-resolution structures of pilus filaments and the machineries that produce them, namely chaperone–usher pili, type IV pili, conjugative type IV secretion pili and type V pili, are beginning to explain… CONTINUE READING
Highly Cited
This paper has 19 citations. REVIEW CITATIONS
Recent Discussions
This paper has been referenced on Twitter 1,220 times over the past 90 days. VIEW TWEETS
11 Citations
133 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 11 extracted citations


Publications referenced by this paper.
Showing 1-10 of 133 references

Structure of a chaperone– usher pilus reveals the molecular basis of rod uncoiling

  • Hospenthal, K M.
  • Cell 164,
  • 2016

Structure of the Neisseria meningitidis type IV pilus

  • S Kolappan
  • Nat. Commun. 7,
  • 2016

Similar Papers

Loading similar papers…