A comprehensive guide to pilus biogenesis in Gram-negative bacteria

@article{Hospenthal2017ACG,
  title={A comprehensive guide to pilus biogenesis in Gram-negative bacteria},
  author={Manuela Kathrin Hospenthal and Tiago R. D. Costa and Gabriel Waksman},
  journal={Nature Reviews Microbiology},
  year={2017},
  volume={15},
  pages={365-379}
}
Pili are crucial virulence factors for many Gram-negative pathogens. These surface structures provide bacteria with a link to their external environments by enabling them to interact with, and attach to, host cells, other surfaces or each other, or by providing a conduit for secretion. Recent high-resolution structures of pilus filaments and the machineries that produce them, namely chaperone–usher pili, type IV pili, conjugative type IV secretion pili and type V pili, are beginning to explain… CONTINUE READING
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