A comprehensive functional analysis of tissue specificity of human gene expression

@article{Dezso2008ACF,
  title={A comprehensive functional analysis of tissue specificity of human gene expression},
  author={Zolt{\'a}n Dezso and Yuri Nikolsky and Evgeny Sviridov and Weiwei Shi and Tatiana Serebriyskaya and Damir Dosymbekov and Andrej Bugrim and Eugene A Rakhmatulin and Richard J. Brennan and Aleksey N. Guryanov and Kelly Wing Man Li and J. J. Blake and Raymond R. Samaha and Tatiana Nikolskaya},
  journal={BMC Biology},
  year={2008},
  volume={6},
  pages={49 - 49}
}
In recent years, the maturation of microarray technology has allowed the genome-wide analysis of gene expression patterns to identify tissue-specific and ubiquitously expressed ('housekeeping') genes. We have performed a functional and topological analysis of housekeeping and tissue-specific networks to identify universally necessary biological processes, and those unique to or characteristic of particular tissues. We measured whole genome expression in 31 human tissues, identifying 2374… CONTINUE READING