A comprehensive evaluation of rodent malaria parasite genomes and gene expression

  title={A comprehensive evaluation of rodent malaria parasite genomes and gene expression},
  author={Thomas Dan Otto and Ulrike B{\"o}hme and Andrew P. Jackson and Martin Hunt and Blandine Franke-Fayard and Wieteke Anna Maria Hoeijmakers and Agnieszka A. Religa and Lauren Poppy Robertson and Mandy J. Sanders and Solabomi A. Ogun and Deirdre A Cunningham and Annette Erhart and Oliver Billker and Shahid M Khan and Hendrik G. Stunnenberg and Jean Langhorne and Anthony A. Holder and Andrew P Waters and Chris I Newbold and Arnab Pain and Matthew Berriman and Chris J Janse},
  booktitle={BMC Biology},
Rodent malaria parasites (RMP) are used extensively as models of human malaria. Draft RMP genomes have been published for Plasmodium yoelii, P. berghei ANKA (PbA) and P. chabaudi AS (PcAS). Although availability of these genomes made a significant impact on recent malaria research, these genomes were highly fragmented and were annotated with little manual curation. The fragmented nature of the genomes has hampered genome wide analysis of Plasmodium gene regulation and function. We have greatly… CONTINUE READING
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The European Malaria Reagent Repository

  • Otto
  • BMC Biology
  • 2014
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