A comprehensive comparison of comparative RNA structure prediction approaches

@article{Gardner2004ACC,
  title={A comprehensive comparison of comparative RNA structure prediction approaches},
  author={Paul P. Gardner and Robert Giegerich},
  journal={BMC Bioinformatics},
  year={2004},
  volume={5},
  pages={140 - 140}
}
An increasing number of researchers have released novel RNA structure analysis and prediction algorithms for comparative approaches to structure prediction. Yet, independent benchmarking of these algorithms is rarely performed as is now common practice for protein-folding, gene-finding and multiple-sequence-alignment algorithms. Here we evaluate a number of RNA folding algorithms using reliable RNA data-sets and compare their relative performance. We conclude that comparative data can enhance… CONTINUE READING
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