A comprehensive clinical review of recombinant human bone morphogenetic protein-2 (INFUSE® Bone Graft)

@article{McKay2007ACC,
  title={A comprehensive clinical review of recombinant human bone morphogenetic protein-2 (INFUSE® Bone Graft)},
  author={William F. McKay and Steven M. Peckham and Jeffrey M. Badura},
  journal={International Orthopaedics},
  year={2007},
  volume={31},
  pages={729-734}
}
The combination of recombinant human bone morphogenetic protein-2 (rhBMP-2) on an absorbable collagen sponge (ACS) carrier has been shown to induce bone formation in a number of preclinical and clinical investigations. In 2002, rhBMP-2/ACS at a 1.5-mg/cc concentration (INFUSE® Bone Graft, Medtronic Spinal and Biologics, Memphis, TN) was FDA-approved as an autograft replacement for certain interbody spinal fusion procedures. In 2004, INFUSE® Bone Graft was approved for open tibial fractures with… CONTINUE READING

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