A comprehensive characterization of rare mitochondrial DNA variants in neuroblastoma


BACKGROUND Neuroblastoma, a tumor of the developing sympathetic nervous system, is a common childhood neoplasm that is often lethal. Mitochondrial DNA (mtDNA) mutations have been found in most tumors including neuroblastoma. We extracted mtDNA data from a cohort of neuroblastoma samples that had undergone Whole Exome Sequencing (WES) and also used snap… (More)
DOI: 10.18632/oncotarget.10271


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