A comprehensive analysis of germline and expressed immunoglobulin repertoire in the horse.

@article{Sun2010ACA,
  title={A comprehensive analysis of germline and expressed immunoglobulin repertoire in the horse.},
  author={Yi Sun and Chunyan Wang and Yating Wang and Tianyi Zhang and Liming Ren and Xiaoxiang Hu and Ran Zhang and Qingyong Meng and Ying Guo and Jing Fei and Ning Li and Yaofeng Zhao},
  journal={Developmental and comparative immunology},
  year={2010},
  volume={34 9},
  pages={1009-20}
}
Based on the recently released horse genome, we have characterized the genomic organization of the horse Ig gene loci. The horse IgH locus in genomic scaffold Un0011 contains 40 D(H) segments, 8 J(H) segments and 50 V(H) segments. The Igkappa locus contains only a single C(kappa) gene, 5 J(kappa) segments and a 60 V(kappa) segments, whereas the Iglambda locus contains 7 C(lambda) genes each preceded by a J(lambda) gene segment. A total of 110 V(lambda) segments with the same transcriptional… CONTINUE READING

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