A comprehensive DNA methylation profile of epithelial-to-mesenchymal transition.

@article{Carmona2014ACD,
  title={A comprehensive DNA methylation profile of epithelial-to-mesenchymal transition.},
  author={Francisco J Carmona and Ver{\'o}nica D{\'a}valos and Enrique Vidal and Antonio G{\'o}mez and Holger Heyn and Yutaka Hashimoto and M. Teresa Vizoso and Anna Mart{\'i}nez-Card{\'u}s and Sergi Sayols and Humberto J. Ferreira and Jose Vicente Sanchez-Mut and Sebastian Moran and M Carmen Margel{\'i} and Eva Castell{\`a} and Mar{\'i}a Berdasco and Olafur Stefansson and Jorunn Erla Eyfjord and Eva Gonz{\'a}lez-Su{\'a}rez and Joaqu{\'i}n Dopazo and Modesto Orozco and Ivo G Gut and Manel Esteller},
  journal={Cancer research},
  year={2014},
  volume={74 19},
  pages={5608-19}
}
Epithelial-to-mesenchymal transition (EMT) is a plastic process in which fully differentiated epithelial cells are converted into poorly differentiated, migratory and invasive mesenchymal cells, and it has been related to the metastasis potential of tumors. This is a reversible process and cells can also eventually undergo mesenchymal-to-epithelial transition. The existence of a dynamic EMT process suggests the involvement of epigenetic shifts in the phenotype. Herein, we obtained the DNA… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 57 references

KasprzykA. BioMart Central Portal—unified access to biological data

S Haider, B Ballester, SmedleyD, J Zhang, RiceP
Nucleic Acids Res • 2009
View 8 Excerpts
Highly Influenced

The Sequence Alignment/Map format and SAMtools

Bioinformatics • 2009
View 10 Excerpts
Highly Influenced

E-Syts, a family of membranous Ca2+-sensor proteins with multiple C2 domains.

Proceedings of the National Academy of Sciences of the United States of America • 2007
View 14 Excerpts
Highly Influenced

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