A component of the multisynthetase complex is a multifunctional aminoacyl-tRNA synthetase.

@article{Cerini1991ACO,
  title={A component of the multisynthetase complex is a multifunctional aminoacyl-tRNA synthetase.},
  author={Claire Cerini and Pierre Kerjan and Martine Astier and Danielle Gratecos and Marc Mirande and Michel S{\'e}m{\'e}riva},
  journal={The EMBO journal},
  year={1991},
  volume={10 13},
  pages={4267-77}
}
In higher eukaryotes, nine aminoacyl-tRNA synthetases are associated within a multienzyme complex which is composed of 11 polypeptides with molecular masses ranging from 18 to 150 kDa. We have cloned and sequenced a cDNA from Drosophila encoding the largest polypeptide of this complex. We demonstrate here that the corresponding protein is a multifunctional aminoacyl-tRNA synthetase. It is composed of three major domains, two of them specifying distinct synthetase activities. The amino and… CONTINUE READING

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