A component of innate immunity prevents bacterial biofilm development

@article{Singh2002ACO,
  title={A component of innate immunity prevents bacterial biofilm development},
  author={Pradeep K. Singh and Matthew R. Parsek and E. Peter Greenberg and Michael J. Welsh},
  journal={Nature},
  year={2002},
  volume={417},
  pages={552-555}
}
Antimicrobial factors form one arm of the innate immune system, which protects mucosal surfaces from bacterial infection. These factors can rapidly kill bacteria deposited on mucosal surfaces and prevent acute invasive infections. In many chronic infections, however, bacteria live in biofilms, which are distinct, matrix-encased communities specialized for surface persistence. The transition from a free-living, independent existence to a biofilm lifestyle can be devastating, because biofilms… 
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