A complex noncoordinate regulation of alpha-lactalbumin and 25 K beta-casein by corticosterone, prolactin, and insulin in long term cultures of normal rat mammary cells.

@article{Ray1986ACN,
  title={A complex noncoordinate regulation of alpha-lactalbumin and 25 K beta-casein by corticosterone, prolactin, and insulin in long term cultures of normal rat mammary cells.},
  author={Durwood B. Ray and Robert W. Jansen and I A Horst and Nancy C. Mills and J. M. L. Kowal},
  journal={Endocrinology},
  year={1986},
  volume={118 1},
  pages={393-407}
}
The concentrations of PRL, corticosterone, and insulin required by long term cultures of normal rat mammary cells to produce alpha-lactalbumin (alpha LA) and the 25,000 mol wt beta-casein were evaluated with a variety of hormone ratios and concentrations. For these studies a double antibody RIA for beta-casein capable of measuring 0.5 ng beta-casein/100 microliter growth media was developed and used along with our previously reported RIA for alpha LA. PRL was active at physiological levels (0… CONTINUE READING
Highly Cited
This paper has 23 citations. REVIEW CITATIONS

Similar Papers

Loading similar papers…