A complex interaction between drug allergy and viral infection.

@article{Shiohara2007ACI,
  title={A complex interaction between drug allergy and viral infection.},
  author={Tetsuo Shiohara and Yoko Kano},
  journal={Clinical reviews in allergy & immunology},
  year={2007},
  volume={33 1-2},
  pages={124-33}
}
A relationship between viral infections and the simultaneous or subsequent development of drug rashes has been observed in a number of clinical situations. We have recently provided evidence to indicate an intimate relationship between reactivation of human herpesvirus 6 (HHV-6) and the development of a severe systemic hypersensitivity reaction referred to as drug-induced hypersensitivity syndrome (DIHS). This syndrome has several unique features that cannot be explained by a drug etiology… CONTINUE READING