A complex ergovaline gene cluster in epichloe endophytes of grasses.

@article{Fleetwood2007ACE,
  title={A complex ergovaline gene cluster in epichloe endophytes of grasses.},
  author={Damien J. Fleetwood and Barry Scott and Geoffrey A. Lane and Aiko Tanaka and Richard D. Johnson},
  journal={Applied and environmental microbiology},
  year={2007},
  volume={73 8},
  pages={2571-9}
}
Clavicipitaceous fungal endophytes of the genera Epichloë and Neotyphodium form symbioses with grasses of the subfamily Pooideae, in which they can synthesize an array of bioprotective alkaloids. Some strains produce the ergopeptine alkaloid ergovaline, which is implicated in livestock toxicoses caused by ingestion of endophyte-infected grasses. Cloning and analysis of a nonribosomal peptide synthetase (NRPS) gene from Neotyphodium lolii revealed a putative gene cluster for ergovaline… CONTINUE READING

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