A complete course of intravenous antibiotics vs a combination of intravenous and oral antibiotics for perforated appendicitis in children: a prospective, randomized trial.

@article{Fraser2010ACC,
  title={A complete course of intravenous antibiotics vs a combination of intravenous and oral antibiotics for perforated appendicitis in children: a prospective, randomized trial.},
  author={Jason D. Fraser and Pablo Aguayo and Charles M. Leys and Scott J. Keckler and Jason G. Newland and Susan W. Sharp and John Patrick Murphy and Charles L. Snyder and Ronald J. Sharp and Walter S Andrews and George W. Holcomb and Daniel J. Ostlie and Shawn David St. Peter},
  journal={Journal of pediatric surgery},
  year={2010},
  volume={45 6},
  pages={
          1198-202
        }
}
INTRODUCTION In a previous prospective randomized trial, we found a once-a-day regimen of ceftriaxone and metronidazole to be an efficient, cost-effective treatment for children with perforated appendicitis. In this study, we evaluated the safety of discharging patients to complete an oral course of antibiotics. METHODS Children found to have perforated appendicitis at the time of laparoscopic appendectomy were enrolled in the study. Perforation was defined as a hole in the appendix or… CONTINUE READING
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