A complete conformational map for RNA.

  title={A complete conformational map for RNA.},
  author={Venkatesh L. Murthy and Rajgopal Srinivasan and David E. Draper and George D. Rose},
  journal={Journal of molecular biology},
  volume={291 2},
A simple stereochemical framework for understanding RNA structure has remained elusive to date. We present a comprehensive conformational map for two nucleoside-5',3'-diphosphates and for a truncated dinucleotide derived from a grid search of all potential conformers using hard sphere steric exclusion criteria to define allowed conformers. The eight-dimensional conformational space is presented as a series of two-dimensional projections. These projections reveal several well-defined allowed and… CONTINUE READING

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