A complement-dependent enzyme immunoassay (C-EIA) with increased sensitivity for IgM-rich rabbit sera.

@article{Kuhn1992ACE,
  title={A complement-dependent enzyme immunoassay (C-EIA) with increased sensitivity for IgM-rich rabbit sera.},
  author={Helena M Kuhn and Lore Brade and Helmut Brade},
  journal={Journal of immunological methods},
  year={1992},
  volume={155 2},
  pages={201-6}
}
An enzyme immunoassay involving activation of complement (C-EIA) was developed for rabbit polyclonal IgM antibodies against lipid A and lipopolysaccharide antigens. C-EIA was significantly higher in sensitivity for IgM-rich rabbit sera compared to EIA using anti-immunoglobulin secondary antibodies. Hence, C-EIA should be useful for the detection of weak IgM… CONTINUE READING