A compendium of proteins that interact with HIF-1α.

@article{Semenza2017ACO,
  title={A compendium of proteins that interact with HIF-1α.},
  author={Gregg L Semenza},
  journal={Experimental cell research},
  year={2017},
  volume={356 2},
  pages={
          128-135
        }
}
Hypoxia-inducible factor 1 (HIF-1) is the founding member of a family of transcription factors that function as master regulators of oxygen homeostasis. HIF-1 is composed of an O2-regulated HIF-1α subunit and a constitutively expressed HIF-1β subunit. This review provides a compendium of proteins that interact with the HIF-1α subunit, many of which regulate HIF-1 activity in either an O2-dependent or O2-independent manner. 

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 12 CITATIONS

HIF-dependent Signaling Pathways in Cancer

VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED