A comparison of treating metabolic acidosis in CKD stage 4 hypertensive kidney disease with fruits and vegetables or sodium bicarbonate.

@article{Goraya2013ACO,
  title={A comparison of treating metabolic acidosis in CKD stage 4 hypertensive kidney disease with fruits and vegetables or sodium bicarbonate.},
  author={Nimrit Goraya and Jan Simoni and Chan-Hee Jo and Donald Everett Wesson},
  journal={Clinical journal of the American Society of Nephrology : CJASN},
  year={2013},
  volume={8 3},
  pages={371-81}
}
BACKGROUND AND OBJECTIVES Current guidelines recommend Na(+)-based alkali for CKD with metabolic acidosis and plasma total CO2 (PTCO2) < 22 mM. Because diets in industrialized societies are typically acid-producing, we compared base-producing fruits and vegetables with oral NaHCO3 (HCO3) regarding the primary outcome of follow-up estimated GFR (eGFR) and secondary outcomes of improved metabolic acidosis and reduced urine indices of kidney injury. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS… CONTINUE READING

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