A comparison of tramadol, amitriptyline, and meperidine for postepidural anesthetic shivering in parturients.

@article{Tsai2001ACO,
  title={A comparison of tramadol, amitriptyline, and meperidine for postepidural anesthetic shivering in parturients.},
  author={Y C Tsai and K S Chu},
  journal={Anesthesia and analgesia},
  year={2001},
  volume={93 5},
  pages={1288-92}
}
UNLABELLED Tramadol is effective for treating shivering during epidural anesthesia in parturients. In addition to its low affinity to opioid receptors, tramadol exerts a modulatory effect on central monoaminergic pathways. In this respect, there are parallels between the mechanisms of the action of tramadol and antidepressants such as amitriptyline. Meperidine is often recommended for the treatment of postanesthetic shivering. This prospective, double-blinded, and randomized clinical study was… CONTINUE READING
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