A comparison of three radionuclide myocardial perfusion tracers in clinical practice: the ROBUST study

@article{Kapur2002ACO,
  title={A comparison of three radionuclide myocardial perfusion tracers in clinical practice: the ROBUST study},
  author={Akhil Kapur and Katherine A. Latus and Glyn Davies and Rhanju T. Dhawan and Sian Eastick and Peter H. Jarritt and George Roussakis and Melanie C. Young and Constantinos Anagnostopoulos and Jimmy Bomanji and Durval C. Costa and Dudley J. Pennell and Elizabeth M. Prvulovich and Peter Joseph Ell and Richard S. Underwood},
  journal={European Journal of Nuclear Medicine and Molecular Imaging},
  year={2002},
  volume={29},
  pages={1608-1616}
}
There are no large studies available to guide the selection of thallium (Tl), methoxyisobutylisonitrile (MIBI) or tetrofosmin (Tf) for myocardial perfusion imaging. Our objective was to compare the technical and clinical performance of the three in routine clinical practice. We randomised 2,560 patients to receive Tl, MIBI or Tf. A 1-day stress/rest protocol was used for MIBI and Tf. Tracer uptake was scored using a 17-segment model, quality and artefact scores were assigned, and ratios of… CONTINUE READING