A comparison of the metabolic fate of phenol, phenyl glucoside and phenyl 6-O-malonyl-glucoside in the rat.


The metabolic fates of 14C-phenol and its model plant conjugates 14C-phenyl glucoside and 14C-phenyl 6-O-malonyl-glucoside have been compared following equimolar oral dosing to rats (1.2 mg phenol/kg). Rapid excretion of radioactivity in the urine (at least 80% within 24 h) was observed with each compound. Phenol was eliminated as expected mainly as phenyl… (More)


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