A comparison of the growth hormone responses to clonidine and apomorphine in the same patients with endogenous depression.

@article{Corn1984ACO,
  title={A comparison of the growth hormone responses to clonidine and apomorphine in the same patients with endogenous depression.},
  author={T. H. Corn and Anthony S Hale and Christopher Thompson and Pamela Bridges and Stuart A. Checkley},
  journal={The British journal of psychiatry : the journal of mental science},
  year={1984},
  volume={144},
  pages={
          636-9
        }
}
The growth hormone responses to clonidine (1.3 micrograms/kgm) and apomorphine (0.005 mg/kgm) have been measured in 8 drug free patients with endogenous depression. In these patients the growth hormone responses to clonidine were significantly smaller than to apomorphine. As these doses of clonidine and apomorphine have previously been reported to cause similar growth hormone responses in normal subjects, these findings support the hypothesis of a defect in the adrenergic but not the… CONTINUE READING