A comparison of the familiality of chronic depression in recurrent early-onset depression pedigrees using different definitions of chronicity.

@article{Mondimore2007ACO,
  title={A comparison of the familiality of chronic depression in recurrent early-onset depression pedigrees using different definitions of chronicity.},
  author={Francis M. Mondimore and Peter P. Zandi and Dean F Mackinnon and Melvin G. McInnis and Erin B. Miller and Barbara A. Schweizer and Raymond P. Crowe and William A. Scheftner and Myrna M. Weissman and Douglas F. Levinson and J Raymond Depaulo and James B. Potash},
  journal={Journal of affective disorders},
  year={2007},
  volume={100 1-3},
  pages={171-7}
}
BACKGROUND The study of chronicity in the course of major depression has been complicated by varying definitions of this illness feature. Because familial clustering is one component of diagnostic validity we compared family clustering of chronicity as defined in the DSM-IV to that of chronicity determined by an assessment of lifetime course of depressive illness. METHODS In 1750 affected subjects from 652 families recruited for a genetic study of recurrent, early-onset depression, we applied… CONTINUE READING
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