A comparison of the effects of raloxifene and conjugated equine estrogen on bone and lipids in healthy postmenopausal women.

@article{Reid2004ACO,
  title={A comparison of the effects of raloxifene and conjugated equine estrogen on bone and lipids in healthy postmenopausal women.},
  author={Ian R Reid and Richard Eastell and Ignac Fogelman and Jonathon D Adachi and Amy L. Rosen and C. J. Netelenbos and Nelson B. Watts and E. R. BernsteinJeffrey I. Seeman and Angelina V Ciaccia and Michael W. Draper},
  journal={Archives of internal medicine},
  year={2004},
  volume={164 8},
  pages={871-9}
}
BACKGROUND Although many studies have assessed the effects of estrogen and raloxifene hydrochloride on bone mineral density and serum lipid concentrations, there are few direct comparative data. METHODS Randomized placebo-controlled trial for 3 years, intention-to-treat analysis. Six hundred nineteen postmenopausal women with prior hysterectomy (mean age, 53.0 years) were studied in 38 centers in Europe, North America, Australasia, and South Africa. They were randomized to 60 mg/d or 150 mg/d… CONTINUE READING