A comparison of the effects of capsaicin with inhibitory nerve stimulation in the rat anococcygeus muscle in vitro.

@article{Davies1998ACO,
  title={A comparison of the effects of capsaicin with inhibitory nerve stimulation in the rat anococcygeus muscle in vitro.},
  author={Robert E. Davies and Patricia Bashforth and Reginald J Docherty},
  journal={European journal of pharmacology},
  year={1998},
  volume={355 2-3},
  pages={
          195-202
        }
}

Biology of the anococcygeus muscle.

The Nitrergic Transmitter of the Anococcygeus: Lessons and Insights

This chapter traces the experimental path that led to the identification of NO as a neurotransmitter in the anococcygeus, and highlights some of the areas of controversy that have developed along the way.

Selective nitrergic neurodegeneration in diabetes mellitus–a nitric oxide‐dependent phenomenon

It is shown by immunohistochemistry that nitrergic nerves undergo selective degeneration since the noradrenergic nerves which have an anti‐erectile function in the penis remained intact and suggested that inhibition of NO synthase is neuroprotective in this condition.

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Neuropeptide-induced contraction and relaxation of the mouse anococcygeus muscle.

Of the peptides studied, only vasoactive intestinal polypeptide caused rapid powerful relaxations in low concentrations; this is consistent with its proposed involvement in nonadrenergic, noncholinergic neurotransmission in the mouse anococcygeus.

The inhibitory modulation of guinea-pig intestinal peristalsis caused by capsaicin involves calcitonin gene-related peptide and nitric oxide

Capsaicin-sensitive afferent neurons do not participate in the neural pathways subserving peristalsis in the guinea-pig small intestine, but modulate peristaltic activity upon stimulation with capsaicin.

THE EFFECTS OF VASOACTIVE INTESTINAL POLYPEPTIDE AND OF ADENOSINE 5′‐TRIPHOSPHATE ON THE ISOLATED ANOCOCCYGEUS MUSCLE OF THE MOUSE

The results suggest that the mechanisms underlying non‐adrenergic, non‐cholinergic inhibitory transmission in the mouse anococcygeus are similar to those in the bovine retractor penis and unlike those inThe guinea‐pig taenia caeci.

The rat anococcygeus muscle and its response to nerve stimulation and to some drugs

The inhibitory response to nerve stimulation is not mimicked by acetylcholine, isoprenaline or ATP, nor blocked by atropine, phentolamine, phenoxybenzamine, propranolol, hexamethonium or lysergic acid diethylamide.

Variable potency of nitrergic‐nitrovasodilator relaxations of the mouse anococcygeus against different forms of induced tone

T Tone induced by all four agents could be relaxed by sodium nitroprusside (SNP), but with a clear order of potency, and the relaxant potency of the nitrergic stimuli was dependent on the agent and mechanism used to induce tone in the preparation.