A comparison of the effects of amphetamine, strychnine and caffeine on prepulse inhibition and latent inhibition.

@article{Bakshi1995ACO,
  title={A comparison of the effects of amphetamine, strychnine and caffeine on prepulse inhibition and latent inhibition.},
  author={V. P. Bakshi and M. A. Geyer and Navid Taaid and N. Swerdlow},
  journal={Behavioural pharmacology},
  year={1995},
  volume={6 8},
  pages={
          801-809
        }
}
Sensorimotor gating deficits characterize several neuropsychiatric disorders, including schizophrenia. Prepulse inhibition (PPI) and latent inhibition (LI) are measures that are used to assess sensorimotor gating and have been found to be reduced in schizophrenia patients. In PPI, a weak stimulus presented immediately prior to a startling stimulus attenuates the startle response. In LI, pre-exposure to a stimulus retards the subsequent association of that stimulus with a consequence (e.g… CONTINUE READING

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