A comparison of the effectiveness of topical tetracycline, benzoyl‐peroxide gel and oral oxytetracycline in the treatment of acne

@article{Norris1991ACO,
  title={A comparison of the effectiveness of topical tetracycline, benzoyl‐peroxide gel and oral oxytetracycline in the treatment of acne},
  author={J. F. B. Norris and Bronwyn R. Hughes and Avril Janette Basey and William James Cunliffe},
  journal={Clinical and Experimental Dermatology},
  year={1991},
  volume={16}
}
A proprietary topical tetracycline preparation (Topicyc‐line) was compared with an alcohol‐based 5% benzoyl‐peroxide gel and with oral oxytetracycline (250 mg twice daily) using a randomized group‐comparative double‐blind study in 69 patients with mild to moderate acne. Facial acne grades improved significantly in all three treatment groups over the 12‐week study period but chest acne grades did not change significantly and only oxytetracycline produced a significant improvement in back grade… 
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