A comparison of the bronchodilator effect of salbutamol inhaled via Turbuhaler as two consecutive doses or as two divided doses at different time intervals.

@article{Lindbladh1999ACO,
  title={A comparison of the bronchodilator effect of salbutamol inhaled via Turbuhaler as two consecutive doses or as two divided doses at different time intervals.},
  author={Christer Lindbladh and Pamela P Smith and Lazette Jackson and B T Begishvilli and Alexander M. Jamieson and Stephen T. Holgate},
  journal={International journal of pharmaceutics},
  year={1999},
  volume={190 1},
  pages={57-62}
}
The aim of the study was to compare the bronchodilatory effect of 2x50 microg salbutamol inhaled via Turbuhaler(R) as two consecutive doses compared with two divided doses (50+50 microg) at different time intervals. The study was of a randomized, double-blind, crossover design. The patients inhaled two doses of 50 microg salbutamol immediately after each other and with a time interval between the doses of 1.5, 3, 5, or 10 mins. Forced expiratory volume in 1 s (FEV(1)) was measured before the… CONTINUE READING