A comparison of the binding profiles of dextromethorphan, memantine, fluoxetine and amitriptyline: Treatment of involuntary emotional expression disorder

@article{Werling2007ACO,
  title={A comparison of the binding profiles of dextromethorphan, memantine, fluoxetine and amitriptyline: Treatment of involuntary emotional expression disorder},
  author={L. Werling and A. Keller and J. Frank and S. Nuwayhid},
  journal={Experimental Neurology},
  year={2007},
  volume={207},
  pages={248-257}
}
  • L. Werling, A. Keller, +1 author S. Nuwayhid
  • Published 2007
  • Biology, Medicine
  • Experimental Neurology
  • We compared the binding profiles of medications potentially useful in the treatment of involuntary emotional expression disorder at twenty-six binding sites in rat brain tissue membranes. Sites were chosen based on likelihood of being target sites for the mechanism of action of the agents in treating the disorder or their likelihood in producing side effects experienced by patients treated with psychoactive agents. We used radioligand binding assays employing the most selective labeled ligands… CONTINUE READING

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