A comparison of rofecoxib versus celecoxib in treating pain after dental surgery: a single-center, randomized, double-blind, placebo- and active-comparator-controlled, parallel-group, single-dose study using the dental impaction pain model.

@article{Malmstrom2002ACO,
  title={A comparison of rofecoxib versus celecoxib in treating pain after dental surgery: a single-center, randomized, double-blind, placebo- and active-comparator-controlled, parallel-group, single-dose study using the dental impaction pain model.},
  author={Kerstin Malmstrom and James R Fricke and Paul N-A Kotey and Barbara Kress and Briggs W Morrison},
  journal={Clinical therapeutics},
  year={2002},
  volume={24 10},
  pages={1549-60}
}
BACKGROUND Rofecoxib and celecoxib, selective cyclooxygenase-2 inhibitors, have analgesic efficacy similar to that of nonselective nonsteroidal anti-inflammatory drugs. OBJECTIVE This study was designed to confirm earlier findings that the overall analgesic efficacy of rofecoxib 50 mg was superior to that of celecoxib 200 mg and to extend the comparison to include celecoxib 400 mg. METHODS In this single-center, randomized, double-blind, placebo- and active-comparator-controlled, parallel… CONTINUE READING

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