A comparison of proliferation markers and their prognostic value for women with endometrial carcinoma. Ki-67, proliferating cell nuclear antigen, and flow cytometric S-phase fraction.

@article{Nordstroem1996ACO,
  title={A comparison of proliferation markers and their prognostic value for women with endometrial carcinoma. Ki-67, proliferating cell nuclear antigen, and flow cytometric S-phase fraction.},
  author={Britta Nordstroem and Peter M Strang and Reinhold Bergstr{\"o}m and Sten B. Nilsson and Bernhard Tribukait},
  journal={Cancer},
  year={1996},
  volume={78 9},
  pages={1942-51}
}
BACKGROUND The understanding of proliferation is a central issue in oncology. Several methods exist for the assessment of the growth fraction and cell-cycle time, but comparative studies that give the clinician advice about the most reliable use of new markers are few. The aim of the current study was to perform methodologic, descriptive, comparative, and prognostic studies of Ki-67, proliferating cell nuclear antigen (PCNA), and flow cytometric S-phase fraction (SPF) in endometrial carcinoma… CONTINUE READING

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