A comparison of physicochemical properties of sterilized chitosan hydrogel and its applicability in a canine model of periodontal regeneration.

@article{Zang2014ACO,
  title={A comparison of physicochemical properties of sterilized chitosan hydrogel and its applicability in a canine model of periodontal regeneration.},
  author={Shengqi Zang and Guangying Dong and Bo Peng and Jie Xu and Zhiwei Ma and Xinwen Wang and Lingxia Liu and Qintao Wang},
  journal={Carbohydrate polymers},
  year={2014},
  volume={113},
  pages={240-8}
}
Chitosan has previously been exploited as a scaffold in tissue engineering processes. To avoid infection, chitosan must be sterilized prior to contact with bodily fluids or blood. Previous research has shown that autoclaved chitosan solution lead to decreased molecular weight, dynamic viscosity, and rate of gelling. We prepared a thermosensitive chitosan hydrogel using autoclaved chitosan powder (121 °C, 10 min) and β-glycerophosphate (chitosan-PA/GP) and compared the physicochemical properties… CONTINUE READING