A comparison of omeprazole with ranitidine for ulcers associated with nonsteroidal antiinflammatory drugs. Acid Suppression Trial: Ranitidine versus Omeprazole for NSAID-associated Ulcer Treatment (ASTRONAUT) Study Group.

Abstract

BACKGROUND Suppressing acid secretion is thought o reduce the risk of ulcers associated with regular use of nonsteroidal antiinflammatory drugs (NSAIDs), but the best means of accomplishing this is uncertain. METHODS We studied 541 patients who required continuous treatment with NSAIDs and who had ulcers or more than 10 erosions in either the stomach or… (More)

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@article{Yeomans1998ACO, title={A comparison of omeprazole with ranitidine for ulcers associated with nonsteroidal antiinflammatory drugs. Acid Suppression Trial: Ranitidine versus Omeprazole for NSAID-associated Ulcer Treatment (ASTRONAUT) Study Group.}, author={Neville D. Yeomans and Zolt Tulassay and L{\'a}szl{\'o} Juh{\'a}sz and Ildiko Racz and J. M. Howard and Christo J. van Rensburg and A J Swannell and Chris J. Hawkey}, journal={The New England journal of medicine}, year={1998}, volume={338 11}, pages={719-26} }