A comparison of methotrexate with placebo for the maintenance of remission in Crohn's disease. North American Crohn's Study Group Investigators.

@article{Feagan2000ACO,
  title={A comparison of methotrexate with placebo for the maintenance of remission in Crohn's disease. North American Crohn's Study Group Investigators.},
  author={Brian G Feagan and Richard N Fedorak and Elizabeth Jan Irvine and Gary Wild and Laura Sutherland and A. Hillary Steinhart and Gordon R. Greenberg and John Koval and Cindy J. Wong and Monica Hopkins and S B Hanauer and J. W. McDonald},
  journal={The New England journal of medicine},
  year={2000},
  volume={342 22},
  pages={1627-32}
}
BACKGROUND Patients with Crohn's disease often have relapses. Better treatments are needed for the maintenance of remission. Although methotrexate is an effective short-term treatment for Crohn's disease, its role in maintaining remissions is not known. METHODS We conducted a double-blind, placebo-controlled, multicenter study of patients with chronically… CONTINUE READING