A comparison of methods to detect publication bias in meta-analysis.

  title={A comparison of methods to detect publication bias in meta-analysis.},
  author={Petra Macaskill and Stephen D. Walter and Les M. Irwig},
  journal={Statistics in medicine},
  volume={20 4},
Meta-analyses are subject to bias for many of reasons, including publication bias. Asymmetry in a funnel plot of study size against treatment effect is often used to identify such bias. We compare the performance of three simple methods of testing for bias: the rank correlation method; a simple linear regression of the standardized estimate of treatment effect on the precision of the estimate; and a regression of the treatment effect on sample size. The tests are applied to simulated meta… CONTINUE READING
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