A comparison of membrane glycoconjugates from mouse cells transformed by murine and primate RNA sarcoma viruses.

@article{Fishman1976ACO,
  title={A comparison of membrane glycoconjugates from mouse cells transformed by murine and primate RNA sarcoma viruses.},
  author={Peter Fishman and Roscoe O. Brady and Steve Aaronson},
  journal={Biochemistry},
  year={1976},
  volume={15 1},
  pages={201-8}
}
Kirsten murine sarcoma virus (Ki-MSV) transformed Balb/eT3 mouse cells (K-Balb) were found to have altered membrane glycoconjugates compared to normal Balb/3T3 cells. There were reduced amounts of mono- and disialogangliosides, GM1 and GD1a, and activity of the specific galactosyltransferase required for synthesis of these gangliosides was reduced to between 0 and 18.5% of normal in the several K-Balb clones examined. When fucose-labeled glycopeptides derived from the surfaces of Balb/3T3 and K… CONTINUE READING