A comparison of levobupivacaine 0.5% and racemic bupivacaine 0.5% for extradural anesthesia for caesarean section.

@article{Faccenda2003ACO,
  title={A comparison of levobupivacaine 0.5% and racemic bupivacaine 0.5% for extradural anesthesia for caesarean section.},
  author={Kathryne A Faccenda and Alison M Simpson and Duncan J Henderson and Drew Smith and Elizabeth M McGrady and Lachlan M M Morrison},
  journal={Regional anesthesia and pain medicine},
  year={2003},
  volume={28 5},
  pages={394-400}
}
BACKGROUND AND OBJECTIVES Bupivacaine is available as a racemic mixture of its enantiomers, dextrobupivacaine and levobupivacaine. Both in vitro and in vivo studies show that dextrobupivacaine has a greater inherent central nervous system (CNS) and cardiovascular toxicity than levobupivacaine. Clinical studies show levobupivacaine to have similar local anesthetic potency to the racemate. The aim of this study was to investigate the clinical efficacy and safety of levobupivacaine compared with… CONTINUE READING