A comparison of ibuprofen and indomethacin for closure of patent ductus arteriosus.

BACKGROUND Indomethacin is the conventional treatment for hemodynamically important patent ductus arteriosus in preterm infants. However, its use is associated with various side effects. In a prospective study, we compared ibuprofen and indomethacin with regard to efficacy and safety for the early treatment of patent ductus arteriosus in preterm infants… CONTINUE READING