A comparison of human smooth muscle and mesenchymal stem cells as potential cell sources for tissue-engineered vascular patches.

@article{Williams2012ACO,
  title={A comparison of human smooth muscle and mesenchymal stem cells as potential cell sources for tissue-engineered vascular patches.},
  author={Corin Williams and Angela W Xie and Sitaram M. Emani and Masayuki Yamato and T. Okano and Joyce Y. Wong},
  journal={Tissue engineering. Part A},
  year={2012},
  volume={18 9-10},
  pages={986-98}
}
In pediatric patients requiring vascular reconstruction, the development of a cell-based tissue-engineered vascular patch (TEVP) has great potential to overcome current issues with nonliving graft materials. Determining the optimal cell source is especially critical to TEVP success. In this study, we compared the ability of human aortic smooth muscle cells (HuAoSMCs) and human mesenchymal stem cells (hMSCs) to form cell sheets on thermoresponsive poly(N-isopropylacrylamide) (PIPAAm) substrates… CONTINUE READING
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