A comparison of hexaminolevulinate fluorescence cystoscopy and white light cystoscopy for the detection of carcinoma in situ in patients with bladder cancer: a phase III, multicenter study.

@article{Fradet2007ACO,
  title={A comparison of hexaminolevulinate fluorescence cystoscopy and white light cystoscopy for the detection of carcinoma in situ in patients with bladder cancer: a phase III, multicenter study.},
  author={Y. F. Fradet and Herbert Barton Grossman and Leonard G. Gomella and Steven L. Lerner and Michael S. Cookson and David Mois Albala and Michael J. Droller},
  journal={The Journal of urology},
  year={2007},
  volume={178 1},
  pages={
          68-73; discussion 73
        }
}
PURPOSE We compared hexaminolevulinate (Hexvix) fluorescence cystoscopy with white light cystoscopy for detecting carcinoma in situ. MATERIALS AND METHODS In this multicenter study 298 patients with known or suspected bladder cancer underwent bladder instillation with 50 ml 8 mM hexaminolevulinate for 1 hour. Cystoscopy was then performed, first using standard white light and then hexaminolevulinate fluorescence cystoscopy. Lesions or suspicious areas identified under the 2 illumination… CONTINUE READING
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