A comparison of epidural bupivacaine-fentanyl and bupivacaine-clonidine in children undergoing the Nuss procedure.

@article{Cucchiaro2006ACO,
  title={A comparison of epidural bupivacaine-fentanyl and bupivacaine-clonidine in children undergoing the Nuss procedure.},
  author={Giovanni Cucchiaro and Scott N. Adzick and J. Bart Rose and Lynne G Maxwell and Mehernoor F Watcha},
  journal={Anesthesia and analgesia},
  year={2006},
  volume={103 2},
  pages={322-7, table of contents}
}
The administration of epidural opioids, though effective for producing analgesia, has severe side effects in most patients. It is unknown whether clonidine can effectively replace opioids and cause fewer side effects. We compared, in this randomized trial, the incidence of vomiting and pruritus as well as the analgesic profile of three different combinations of bupivacaine, fentanyl, and clonidine administered epidurally in patients undergoing the Nuss procedure: bupivacaine + fentanyl… CONTINUE READING