A comparison of enzyme immunoassay and polymerase chain reaction with the clinical examination for diagnosing ocular herpetic disease.

@article{Kowalski1993ACO,
  title={A comparison of enzyme immunoassay and polymerase chain reaction with the clinical examination for diagnosing ocular herpetic disease.},
  author={Regis Paul Kowalski and Yitzchak J. Gordon and Eric G. Romanowski and T P Araullo-Cruz and Paul R Kinchington},
  journal={Ophthalmology},
  year={1993},
  volume={100 4},
  pages={530-3}
}
PURPOSE The results of two laboratory diagnostic herpes simplex virus (HSV) tests, an enzyme immunoassay (improved Herpchek [iHC]) and the polymerase chain reaction (PCR), were compared with the clinical examination in the diagnosis of HSV. We determined when diagnostic laboratory tests provided the initial diagnosis of HSV ocular disease and when they were only confirmatory. METHODS The sensitivity and specificity of iHC and PCR were determined using 22 HSV culture-positive clinical samples… CONTINUE READING

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