A comparison of efficacy and tolerance of the short acting sedatives midazolam and zopiclone.

@article{Begg1992ACO,
  title={A comparison of efficacy and tolerance of the short acting sedatives midazolam and zopiclone.},
  author={Evan James Begg and Richard A. Robson and C M Frampton and Janis E. Campbell},
  journal={The New Zealand medical journal},
  year={1992},
  volume={105 944},
  pages={428-9}
}
AIMS To compare the efficacy and tolerance of midazolam, 15 mg and zopiclone 7.5 mg once daily for seven days in a prospective, double blind trial of 88 patients, aged 18 or over, with sleep disorders in general practice. METHODS Efficacy was evaluated using the Leeds sleep evaluation questionnaire (LSEQ). Adverse reactions were recorded as volunteered. RESULTS fifty-one patients completed all aspects of the trial without violation of the protocol. Patients taking zopiclone improved in all… CONTINUE READING