A comparison of differentiation protocols for RGC-5 cells.

  title={A comparison of differentiation protocols for RGC-5 cells.},
  author={J. Wood and G. Chidlow and Tuyet Tran and J. Crowston and R. Casson},
  journal={Investigative ophthalmology & visual science},
  volume={51 7},
  • J. Wood, G. Chidlow, +2 authors R. Casson
  • Published 2010
  • Biology, Medicine
  • Investigative ophthalmology & visual science
  • PURPOSE. Although the RGC-5 cell line is widely used in retinal ganglion cell (RGC) research, recent data have raised questions about the nature of these cells. The authors performed a systematic analysis of RGC-5 cells to determine which RGC or neuronal markers are expressed after treatment with known differentiating agents, thus providing further insight into the nature of these cells and assisting in defining their future use. METHODS. RGC-5 cells were treated for 5 days with staurosporine… CONTINUE READING
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